Clinical Trials
When the current standard of care does not offer satisfactory results for a particular type of disease, doctors and medical researchers try to figure out new means of treatment, either new medication or procedures, or new combinations or approaches based on existing ones.
A clinical trial (or clinical study) is a real-life assessment of the efficiency of the new treatment in curing patients. For the patients participating in the study, if it proves effective, it is an invaluable opportunity to benefit from the novel treatment — especially when time is an important factor because of the progression of the disease.
Dr. Doru Paul is lead investigator for the following clinical trials. If you are a cancer patient and need further information about these clinical studies please call (646) 962-6200 and set up an appointment at his office at Weill Cornell Medicine, New York.
Efficacy and Safety of Pembrolizumab Plus Lenvatinib in Previously Treated Participants With Select Solid Tumors
A Phase 3 study trying to provide a higher chance of cure for patients with unresectable or metastatic squamous cell cancer of head and neck than the current standard of care.
Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma
A Phase 3 study trying to increase the chances of cure for patients with localized squamous cell cancer of head and neck. Features Pembrolizumab given prior to surgery and in combination with radiotherapy given post-surgery.
Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease
A unique study that uses three different immunotherapy approaches in order to increase the chance of cure of patients with recurrent localized or oligometastatic squamous cell cancer of head and neck.